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Especially in the last century, most Western countries have experienced significant demographic changes with a continuing increase in the number of older people who face medical and functional challenges, as well as diseases including obesity, cardiovascular hearth diseases (CHD) or type 2 diabetes mellitus are caused by civilization. The World Health Organization has identified these three diseases are the most severe noncommunicable disease (NCD) causing problems today´s Western World. Noncommunicable diseases are mostly diseases of slow progression and normally of long duration.
Most NCDs primarily result from unhealthy lifestyles including the consumption of too much or unhealthy food, too much alcohol and excessive smoking habits, combined with physical inactivity. More specifically inactivity and unhealthy eating habits associated with weight gain, overweight and obesity are the major underlying causes for modern diseases such as CHD or type 2 diabetes mellitus.
Many cross-sectional and intervention studies have focused on the relationship between an unhealthy lifestyle e.g. physical inactivity, unhealthy eating behaviors, smoking and alcohol consumption, and diseases in different study groups, e.g. high risk groups or different age groups. All in all, cross-sectional studies suggest that physical activity may be an important factor for improving the general health and preventing the development of, among others, the above mentioned NCDs. Although these diseases are very prominent in many western countries only few longitudinal studies exist that focus on their development during a person´s lifetime and their association with other habitual factors such as physical activity.
Because NCDs develop over a long period and may have many causes, understanding the progress of these diseases and their association with habitual factors such as physical activity is important for elaborating long- term prevention programs and guidelines. To investigate their development, longitudinal studies, with healthy persons, i.e. persons without obvious diseases at baseline examination and long-term epidemiological view as necessary.
Overall, the results of the reviewed articles provide a general view about the longitudinal relationship between physical activity and the incidence of NCD and health problems. Physical activity seems to be a relevant factor for preventing age-related diseases; however more long-term research is necessary. Retrieved and adapted from Reiner, M, Niermann C, Jekau, D. et al. Long Term- health benefits of physical activity – a systematic review of longitudinal studies. BMC Public Health 13, 813 (2013) 1
● A research report ● A novel ● A magazine opinion article ● A case study report (^1) https://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-13-
● Research has to be developed on specific subgroups that do not manifest any associated symptoms.
Schizophrenia is persistent and disabling psychotic illness that ruins the lives of patients and their families. It affects emotion, behavior, perception and sleep disturbances among others although these symptoms are not specific to schizophrenia
Sleep is the state of temporary decreased awareness of environmental stimuli and characterized by relative unconsciousness of the external world. It is a biological process which is crucial to the maintenance of mental and physical health. Sleep quality is satisfaction with sleep experience and integrating aspects of sleep initiation sleep maintenance, sleep quantity and refreshment upon awakening which is relevant to optimal health and functioning4. People with schizophrenia have been identified to experience sleep disorders at relatively higher rates than general population and sleep problems including difficulty falling asleep and maintaining it are common in these subjects
Short sleep duration (generally less than 7 hours) reported as an important risk factor for different adverse outcomes and can raises rates of mortality. Decreased and non- restorative sleep is common complaints among people with mental illness and affects up to 30-80% of schizophrenic patients. Likewise, repeated disturbance of sleep cycle or
Muni Rubens, Venkataraghavan Ramamoorthy, Anshul Saxena, Nancy Shehadeh, Sandeep Appunni, “HIV Vaccine: Recent advances, Current Roadblocks, and Future Directions”, Journal of Immunology Research, vol 2015, Article ID 560347, 9 pages, 2015. 3
● Vaccines would be tested and researched quite before 1986 ● Preliminary vaccines testing will be ready after 1986