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The hypothesis to explain enzyme– substrate complex formation:

0 votes

February 14th, 2013 13:09
in Biochemistry by gaurishaknar (Aquinas College (TN), Electrical Engineering)

The hypothesis to explain enzyme– substrate complex formation:

(A) Lock and key model (B) Induced fit theory (C) Proenzyme theory (D) Both (A) and (B)

1 Answers
0 votes

March 9th, 2013 08:20
sajid (Shree Ram Swarup College of Engineering & Management , Investment management)
"(C) Proenzyme theory (a) Lock and Key model(Fischer’s Templatetheory): The substrate fits to active site of anenzyme just as a key fits into a proper lock. Thus,the active site of the enzyme is rigid andpreshaped where only a specific substrate canbind.(b) Induced fit theory (Koshl and model): As perthis, the substrate induces a conformationa LC hange in the enzyme resulting in the formationof substrate binding (active) site."

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